Gel purification is the most economical way to purify oligonucleotides for research needs. It is currently the best purification choice for longer oligonucleotides (>35 bases) and for oligonucleotides in which secondary structure may substantially interfere with HPLC purification.
A gel photograph is sent with each gel purified oligo.
Standard HPLC Purification
HPLC purification is performed using strong anion exchange (SAX) chromatography. This process allows oligos to be purified to specific and repeatable purity levels. HPLC purified oligos can be specified to the following levels (as assessed by analytical AX-HPLC):
Research Grade: > 80% Full Length
Level I: > 90% Full Length
Level II: > 95% Full Length
Gel photograph and analytical HPLC traces are included. A High Performance Capillary Electrophoresis (HPCE) is included for phosphorothioated oligos.